程杨洋，特聘副研究员。先后入选西安交通大学人才计划和304永利集团官网入口“双百人才工程计划”。2008-2017年就读于304永利集团官网入口化学学院，获得有机化学博士学位，师从游劲松教授；随后赴瑞士日内瓦大学开展博士后研究，师从Stefan Matile教授；2021年入职西安交通大学医学部；2025年加入304永利集团官网入口国家生物医学材料工程技术研究中心。迄今已在多领域国际权威学术期刊上发表SCI论文35篇，以第一/通讯作者在J. Am. Chem. Soc.（2篇）、Angew. Chem. Int. Ed.（2篇）、Adv. Funct. Mater.、Chem. Sci.、J. Med. Chem.、J. Control. Release、Chem. Eng. J.、Chem. Mater. 等期刊发表16篇，论文累计他引1400余次，平均影响因子12.2，h因子19；主持国家自然科学基金、校级人才计划等项目，累计科研经费190万元；发表专利3项；担任《Chinese Chemical Letters》（中国化学快报）青年编委。
主要研究方向：纳米药物的开发与应用、大分子递送策略的开发与应用、生物医用水凝胶的开发与应用
招生专业：生物医学工程、有机化学、材料学、药学
联系方式：304永利集团官网入口望江校区生物材料楼，邮箱: yycheng@scu.edu.cn
代表性论文
1. Y. Cheng, L. Zong, J. López-Andarias, E. Bartolami, Y. Okamoto, T. Ward, N. Sakai, S. Matile*. Cell-Penetrating Dynamic-Covalent Benzopolysulfane Networks. Angew. Chem. Int. Ed. 58 28 2019:9522
2. Y. Cheng, G. Li, Y. Liu, Y. Shi, G. Gao*, D. Wu, J. Lan, J. You*. Unparalleled Ease of Access to a Library of Biheteroaryl Fluorophores via Oxidative Cross-Coupling Reactions: Discovery of Photostable NIR Probe for Mitochondria. J. Am. Chem. Soc. 138 14 2016:4730
3. Y. Cheng, Y. Wu, G. Tan, J. You*. Nickel Catalysis Enables Oxidative C(sp2)–H/C(sp2)–H Cross-Coupling Reactions between Two Heteroarenes. Angew. Chem. Int. Ed. 55 40 2016:12275
4. J. Wu#, Y. Cheng#, J. Lan*, D. Wu, S. Qian, L. Yan, Z. He, X. Li, K. Wang, B. Zou*, J. You*. Molecular Engineering of Mechanochromic Materials by Programmed C–H Arylation: Making a Counterpoint in the Chromism Trend. J. Am. Chem. Soc. 138 39 2016:12803
5. J. Liu, R. Zhang, Y. Bao, Y. Chen, W. Zheng, Z. Zhang, P. Chen, M. Ji, Y. Cheng*, P. Hou*, D. Ding, C. Chen*. Highly Efficient and Universal Degradation of PD-L1 via Mitochondrial Oxidative Stress Evoked by Cationic AIE-Active Photosensitizers for Cancer Immunotherapy. Adv. Funct. Mater. 35 7 2025:2414495
6. Y. Tan, S. Zhang, Y. Cheng*, S. Zhang*. Cross-Linked Selenolipoic Acid Nanoplatform Modulates Intracellular and Extracellular Reactive Oxygen Species for Cancer Immunotherapy. J. Control. Release 386 2025:114130
7. S. Wang, M. Sui, Q. Chen, J. Guo, H. Yang, Y. Zhou, M. Ji, Y. Cheng*, P. Hou*. Engineering PD-L1 Targeted Liposomal Canagliflozin Achieves Multimodal Synergistic Cancer Therapy. Chem. Eng. J. 498 2024:155074
8. Y. Cheng, A. Pham, T. Kato, B. Lim, D. Moreau, J. López-Andarias, L. Zong, N. Sakai, S. Matile*. Inhibitors of Thiol-Mediated Uptake. Chem. Sci. 12 (2) 2021:626
9. Z. Zeng, Z. Yang, C. Li, S. Liu, W. Wei, Y. Zhou, S. Wang, M. Sui, M. Li, S. Lin*, Y. Cheng*, P. Hou*. Advancing Cancer Immunotherapy through Engineering New PD-L1 Degraders: A Comprehensive Study from Small Molecules to PD-L1-Specific Peptide-Drug Conjugates. J. Med. Chem. 67 (21) 2024:19216
